Posted by Guru
"Whats wrong with creatine?"
Yeah, nothing new to me. Of course creatine is unstable. If it was too stable it wouldn't phosphorylate ADP.
One point I want to add to the "what's wrong with creatine" section of that site (and this is a pet peeve of mine, being a scientist) is that they are basically doing what every other company does. Try to make it look like they've done their homework and are smarter than the rest, but these guys failed as well.
Here is the statementMany companies rely on testing methods such as HPLC (High Performance Liquid Chromatography) to guarantee their creatine products are 100% stable and pure.
However, these products are only tested while they are dry. As soon as you add them to a liquid, the story changes dramatically!
Does anyone else see the problem? Well, HPLC is not a test done on dry compounds. The compounds are indeed in water.... for a long time too. Even without knowing how the assay works, just look at the name for God sakes. HPLC (the L stands for "liquid").
My point, if the creatine survies the HPLC assay, then it will survive the few seconds in your glass. The question is whether it survives the route from your stomach to your muscles. Indeed it should because we obtain a lot of our creatine from red meat.
All in all, what I am saying doesn't change the fact that creatine is hard on your kidneys, whether it is creatine or creatinine.
Man, I need to write a book.