Caesar's Palace and The Venetian are my two favorites on the strip. Both have good clubs and restaurants. Both have the sky painted on their ceilings, which creates a cool/trippy effect the later/more intoxicated you get. I would recommend Casa Fuente in Caesars, its a cigar bar that carries some dank handmades. Also, I definitely recommend hitting up the sports book at Caesar's and putting some dough on the fights on Friday

Really you cant go wrong if you are in Vegas though! I'm having fear and loathing style flashbacks right now....